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EBTATE

EBTATE incorporates Evans Blue (EB) in the somatostatin analog backbone which significantly increases residence in albumin, a virtual slow release system. Conjugating a targeting molecule to Evans Blue (EB =albumin-binding motif) prolongs half-life in blood, enhancing theranostic bioavailability. In a head-to-head comparison, long-acting EBTATE showed favorable in vivo pharmacokinetics and anti-tumor efficacy vs. TATE.

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